Senior Scientist, Cell Biology Mechanistic Biology and Profiling

Job Description

Job Ttitle: Senior Scientist, Cell Biology Mechanistic Biology and Profiling

Company: AstraZeneca


Description: This is an exciting opportunity for a dedicated scientist with expertise in cell biology assay development and execution to play a pivotal role in drug discovery projects within AstraZeneca R&D in Waltham, MA. You will collaborate with scientists with varied backgrounds on drug discovery projects primarily within Oncology. Working collaboratively in project teams, you will help identify and develop high-quality lead compounds that can progress to clinical candidate drugs. You will support multiple projects simultaneously as part of a dynamic multidisciplinary team environment.AccountabilitiesIn this lab-based position, you will develop, validate, and use cell biology based functional assays to rapidly profile compounds to inform chemistry enabling projects to move quickly. Responsibilities include:Deliver high quality compound screening data from cell-based functional assays to inform project drug designDevelop and validate cell-based functional assays to meet project needsMaintain working knowledge of advances in cell-based assays for drug discovery/profilingPresent scientific data and insights at group and departmental meetings, contributing technical expertise in areas of responsibilityContribute to multiple drug project teams in a fast-paced environmentWork as a great teammate to ensure delivery of quality leads for drug discovery projectsEssential Skills/ExperiencePh.D. or equivalent in Cell Biology, Biology, or a related field with 1-3 years post-graduate experience ORMasters Degree with 5-8 years of post-graduate experienceStrong team player with good written and oral communication skillsRobust track record culturing a variety of cellsHistory of successful development and implementation of cell-based functional assays such as AlphaLISAs, HiBiTs, nanoBRETs, proliferation assays, and imaging assaysExtensive experience with a variety of imaging platforms/technologiesPropensity to tackle challenges creatively and contribute and improve assay technologies and processesAbility to record protocols and experiments in timely manner and maintain excellent laboratory notebookProficient in Microsoft Excel, Word, and PowerPointExceptional critical thinking, troubleshooting, and problem-solving skillsDesirable Skills/ExperienceExperience in pharma/biotechExperience in supporting oncology programs/projectsPast work with culturing primary human cells/organoidsAt AstraZeneca, we are committed to following the science to explore and innovate. Join our team as we work towards treating, preventing, modifying, and even curing some of the world’s most sophisticated diseases. Our inclusive environment fosters collaboration with academia and biotech, empowering us to make bold decisions and celebrate our successes and failures along the way. By integrating our diverse knowledge from various fields, we create the greatest impact on disease.About the Waltham SiteOur Waltham, Massachusetts facility develops life changing small-molecule research in North America, with innovative laboratories at the Gatehouse Park BioHub, just west of the city center. Our BioHub facility, is a bold new R&D initiative, which fosters life science discoveries and the exchange of ideas. Here, we play host to some of the most innovative technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration. With a shuttle bus to and from Alewife station, the location provides you the ability to work in the heart of one of the world’s most vibrant research centers.Our Waltham site offers a variety of amenities to help book productivity and help keep our employees happy and engaged. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you’ll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams and the greater research community.As AstraZeneca continues to put patients at the forefront of our mission, we are excited for our move to Kendall Square/Cambridge in 2026. Find out more information here:Competitive remuneration and benefits applyWe offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.If you are passionate about science and want to be part of a team that makes a significant impact on patients’ lives, apply now!Date Posted 07-Jan-2025Closing Date 17-Jan-2025Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

Salary:

Location: Waltham, MA

Date: Thu, 09 Jan 2025 08:46:32 GMT


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